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Analyzing Sequence Data using the GENESIS Package12 months ago
Overview | Convert VCF to GDS | Create a SeqVarData object | Population structure and relatedness | KING | PC-AiR | PC-Relate | Association tests | Null model | Single variant tests | Aggregate tests | References
Preparing Affymetrix Data3 years ago
Overview | Creating the SNP Annotation Data Object | Creating the Scan Annotation Data Object | Creating the Data Files | Genotype Files | Creating the Genotype file | Intensity Files | Creating the quality file | Creating the Intensity file | BAlleleFrequency and LogRRatio Files | Creating the BAlleleFrequency and LogRRatio file
Genetic Association Testing using the GENESIS Package5 years ago
Overview | Data | Preparing Scan Annotation Data | Reading in Genotype Data | R Matrix | GDS files | PLINK files | HapMap Data | Reading in the GRM from PC-Relate | Mixed Model Association Testing | Fit the Null Model | Quantitative Phenotypes | Multiple Fixed Effect Covariates | Multiple Random Effects | Heterogeneous Residual Variances | Binary Phentoypes | Run SNP-Phenotype Association Tests | Output | The Null Model | The Association Tests | Heritability Estimation | References
Population Structure and Relatedness Inference using the GENESIS Package5 years ago
Overview | Principal Components Analysis in Related Samples (PC-AiR) | Relatedness Estimation Adjusted for Principal Components (PC-Relate) | Data | Reading in Genotype Data | R Matrix | GDS files | PLINK files | HapMap Data | LD pruning | Pairwise Measures of Ancestry Divergence | Running PC-AiR | Reference Population Samples | Partition a Sample without Running PCA | Output from PC-AiR | Plotting PC-AiR PCs | Running PC-Relate | Output from PC-Relate | References
Iterators in SeqVarTools7 years ago
Data formats in GWASTools8 years ago
GWAS Data Cleaning8 years ago
Introduction to SeqVarTools9 years ago